Monday, January 25, 2016

GEDmatch explained 1

GEDmatch is a free website where people can compare their chromosomes to each other and find out if they share enough DNA to be related to each other "during historical time", which is from around 1600 to the present day.

The 1st feature of GEDmatch that you get to use is "one-to-one" compare.  You will need to use that "tool" a lot.
Open "one-to-one".  Put your Kit number, that GEDmatch gave you after your upload was finished, in one box, and put someone else's number in the other. You might get:
Comparing Kit Axxxxxxx(Janice Jxxxxxxx) and Fxxxxxxx (Anatoly Nxxxxx)


Minimum threshold size to be included in total = 700 SNPs
Mismatch-bunching Limit = 350 SNPs
Minimum segment cM to be included in total = 7.0 cM


ChrStart LocationEnd LocationCentimorgans (cM)SNPs
341,191,49255,638,6339.82,812
Largest segment = 9.8 cM
Total of segments > 7 cM = 9.8 cM
Estimated number of generations to MRCA = 5.4

NOTICE that your info is open to anyone who is DNA related to you, or knows your Kit #.  So you may want to use an alias and a new email for GEDmatch.   

Some definitions:
        SNPs: single nucleotide pairs. DNA is like a ladder, the rungs are composed of 4 nucleotides: C, T, A, G.  The order that the nucleotides are in is the actual code that make you.
            Chr: chromosome.  This match is on chromosome 3

REMEMBER THAT YOU HAVE 2  of every autosome!!!
So if someone else comes along that matches you at that spot, you will have to run one-to-one to each other.

Centimorgans:  1/100 of a "Morgan". A Morgan is the length of DNA that would experience a cross-over (See post: 'Basic Human Genetics 2' for info on cross-overs) 1% per generation.  A centiMorgan would experience 0.01% per generation.

GEDmatch sets their limit of relatedness to 7.0 cM and 700 SNP's.  Other DNA sites have different thresholds, Ancestry's is more liberal.

MCRA: most recent common ancestor.  GEDmatch tends to be rather liberal with this.  Add 2 generations, this is the actual range one would expect to find the common ancestor.  In this example: 5.4 to 7.4 generations.







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